Methoxetamine (MXE) is a synthetic drug with mainly dissociative (dissociation of body and mind) and psychedelic (sensory distortions and hallucinations) properties.
Methoxetamine is one of the new synthetic drugs (“designer drugs,” “research chemicals,” “legal highs”) that are sold online. It often sold either as ketamine or as one of its derivatives. However, the effects of MXE are different from those of ketamine: they take longer to appear, they are more potent and longer-lasting (see below). Chemically, methoxetamine is close to narcotic drugs such as ketamine and phencyclidine (PCP). Buy Methoxetamine(MXE) Online
The hydrochloride salt of methoxetamine is a white, odorless crystalline powder at room temperature. A physical description of the freebase form could not be found in readily accessible literature.
In research examining the pharmacological profile, data suggests that methoxetamine has affinity for the N-methyl-D-aspartate (NMDA) receptor and acts as an antagonist.
Also, it is similar to the related ketamine but it has a longer duration of action than that of ketamine..
In addition similarly to ketamine, methoxetamine also involves dopamine and serotonin reuptake inhibition.
For instance no studies have performed examining the pharmacology and mode of action of methoxetamine in humans.
There are no published formal animal or human studies examining the pharmacokinetic properties of MXE.
Users report rapid onset of action (10-20 minutes) following nasal insufflation, rectal or intravenous/intramuscular administration.
Therefore the sublingual route reported as less effective, with oral least effective.
Above all there are a few reports of effects lasting 24 hours; the half-life for clinical effects is three hours .